Our laboratory is part of the Department of Radiology, Center for Advanced Imaging Innovation and Research, New York University School of Medicine. We are fortunate to benefit from state-of-the-art facilities and equipment as well as a strong and vibrant research community.
Our research focuses on the development and evaluation of new hardware and software that allows us to perform high quality multinuclear magnetic resonance measurements in the human tissue. Multinuclear magnetic resonance imaging (MRI) and spectroscopy (MRS) can assess metabolic function in the human tissue. Phosphorus (31P) MR can probe specific biological processes directly involved in mitochondrial energy metabolism. Impairments in energy metabolism occur in many diseases including type 2 diabetes, Alzheimer’s disease, bipolar disorders, and schizophrenia, and can lead to complications such as cognitive impairment or limb amputation.
Through the development of new, highly sensitive, and quantitative MR techniques we have a unique opportunity to improve our understanding of metabolic abnormalities associated with many diseases, identify new targets for treatment, and test efficacy of new pharmacological agents.